2490676-19-0
2490676-19-0 structure
- Name: FTX-6058 hydrochloride
- Chemical Name: FTX-6058 hydrochloride
- CAS Number: 2490676-19-0
- Molecular Formula: C22H19ClFN5O2
- Molecular Weight: 439.87
- Catalog: Signaling Pathways Epigenetics Histone Methyltransferase
- Create Date: 2021-11-01 17:49:31
- Modify Date: 2024-01-03 13:27:02
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FTX-6058 hydrochloride is a potent and orally active inhibitor of Embryonic Ectoderm Development (EED). FTX-6058 hydrochloride can induce HbF protein expression in cell and murine models. FTX-6058 hydrochloride can be used for the research of select hemoglobinopathies, including sickle cell disease and β-thalassemia[1][2].
| Name | FTX-6058 hydrochloride |
|---|
| Description | FTX-6058 hydrochloride is a potent and orally active inhibitor of Embryonic Ectoderm Development (EED). FTX-6058 hydrochloride can induce HbF protein expression in cell and murine models. FTX-6058 hydrochloride can be used for the research of select hemoglobinopathies, including sickle cell disease and β-thalassemia[1][2]. |
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| Related Catalog | |
| In Vitro | FTX-6058 hydrochloride inhibits PRC2 via binding to EED, which induces robust HbF protein expression in both cell and murine models[2]. |
| References |
[1]. Boerner LK. Virtual meeting delivers first time drug structures. April 12, 2021. |
| Molecular Formula | C22H19ClFN5O2 |
|---|---|
| Molecular Weight | 439.87 |