1794942-12-3

1794942-12-3 structure

Name: Maprotiline-d5 hydrochloride
Chemical Name: Maprotiline-d5 hydrochloride
CAS Number: 1794942-12-3
Molecular Formula: C₂₀H₁₉D₅ClN
Molecular Weight: 318.90
Catalog: Signaling Pathways Autophagy Autophagy
Create Date: 2021-10-11 10:25:04
Modify Date: 2024-01-12 16:05:30
Maprotiline-d5 hydrochloride is the deuterium labeled Maprotiline hydrochloride. Maprotiline hydrochloride is a selective noradrenalin re-uptake inhibitor and a tetracyclic antidepressant[1][2].

Name	Maprotiline-d5 hydrochloride

Description	Maprotiline-d5 hydrochloride is the deuterium labeled Maprotiline hydrochloride. Maprotiline hydrochloride is a selective noradrenalin re-uptake inhibitor and a tetracyclic antidepressant[1][2].
Related Catalog	Signaling Pathways >> Autophagy >> Autophagy Research Areas >> Neurological Disease
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Peng, W.H., et al., Berberine produces antidepressant-like effects in the forced swim test and in the tail suspension test in mice. Life Sci, 2007. 81(11): p. 933-8. [3]. http://en.wikipedia.org/wiki/Maprotiline

Molecular Formula	C₂₀H₁₉D₅ClN
Molecular Weight	318.90

Hazard Codes	Xn