1217657-97-0

1217657-97-0 structure

Name: N-Methyl duloxetine-d7
Chemical Name: N-Methyl duloxetine-d7
CAS Number: 1217657-97-0
Molecular Formula: C₁₉H₁₄D₇NOS
Molecular Weight: 318.48
Catalog: Signaling Pathways Membrane Transporter/Ion Channel Sodium Channel
Create Date: 2021-11-09 12:51:32
Modify Date: 2024-01-22 16:09:14
N-Methyl duloxetine-d7 is the deuterium labeled N-Methyl Duloxetine. N-Methyl Duloxetine is an analgesic. N-Methyl Duloxetine elicits both tonic and use-dependent block of neuronal Na+ channels[1][2].

Name	N-Methyl duloxetine-d7

Description	N-Methyl duloxetine-d7 is the deuterium labeled N-Methyl Duloxetine. N-Methyl Duloxetine is an analgesic. N-Methyl Duloxetine elicits both tonic and use-dependent block of neuronal Na+ channels[1][2].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> Sodium Channel Research Areas >> Neurological Disease
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Wang CF, et al. R-Duloxetine and N-Methyl Duloxetine as Novel Analgesics Against ExperimentalPostincisional Pain. Anesth Analg. 2016 Mar;122(3):719-29.

Molecular Formula	C₁₉H₁₄D₇NOS
Molecular Weight	318.48