1352993-39-5

1352993-39-5 structure

Name: Trazpiroben
Chemical Name: 3-{[1-Cyclohexyl-4-oxo-8-(4-oxo-4-phenylbutyl)-1,3,8-triazaspiro[4.5]dec-3-yl]methyl}benzoic acid
CAS Number: 1352993-39-5
Molecular Formula: C₃₁H₃₉N₃O₄
Molecular Weight: 517.66
Catalog: Signaling Pathways GPCR/G Protein Dopamine Receptor
Create Date: 2021-12-22 07:53:16
Modify Date: 2024-01-14 22:29:14
Trazpiroben (TAK-906) is a dopamine D2/D3 receptor antagonist used for chronic research of moderate-to-severe gastroparesis[1].

Name	3-{[1-Cyclohexyl-4-oxo-8-(4-oxo-4-phenylbutyl)-1,3,8-triazaspiro[4.5]dec-3-yl]methyl}benzoic acid
Synonyms	3-{[1-Cyclohexyl-4-oxo-8-(4-oxo-4-phenylbutyl)-1,3,8-triazaspiro[4.5]dec-3-yl]methyl}benzoic acid Benzoic acid, 3-[[1-cyclohexyl-4-oxo-8-(4-oxo-4-phenylbutyl)-1,3,8-triazaspiro[4.5]dec-3-yl]methyl]-

Description	Trazpiroben (TAK-906) is a dopamine D2/D3 receptor antagonist used for chronic research of moderate-to-severe gastroparesis[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Dopamine Receptor Signaling Pathways >> Neuronal Signaling >> Dopamine Receptor Research Areas >> Neurological Disease
References	[1]. Kuo B, Scimia C, Dukes G, Zhang W, Gupta S, Chen C, Chuang E, Camilleri M. Randomised clinical trial: safety, pharmacokinetics and pharmacodynamics of trazpiroben (TAK-906), a dopamine D2 /D3 receptor antagonist, in patients with gastroparesis. Aliment Pharmacol Ther. 2021 Aug;54(3):267-280.