2382768-55-8

2382768-55-8 structure

Name: (32-Carbonyl)-RMC-5552
Chemical Name: (32-Carbonyl)-RMC-5552
CAS Number: 2382768-55-8
Molecular Formula: C₉₃H₁₃₄N₁₀O₂₄
Molecular Weight: 1776.11
Catalog: Signaling Pathways PI3K/Akt/mTOR mTOR
Create Date: 2021-12-19 22:17:42
Modify Date: 2025-08-26 18:31:29
(32-Carbonyl)-RMC-5552 is a potent mTOR inhibitor. (32-Carbonyl)-RMC-5552 inhibits mTORC1 and mTORC2 substrate (p-P70S6K-(T389), p-4E-BP1-(T37/36), AND p-AKT1/2/3-(S473)) phosphorylation with pIC50s of > 9, >9 and between 8 and 9, respectively (patent WO2019212990A1, example 2)[1].

Name	(32-Carbonyl)-RMC-5552

Description	(32-Carbonyl)-RMC-5552 is a potent mTOR inhibitor. (32-Carbonyl)-RMC-5552 inhibits mTORC1 and mTORC2 substrate (p-P70S6K-(T389), p-4E-BP1-(T37/36), AND p-AKT1/2/3-(S473)) phosphorylation with pIC50s of > 9, >9 and between 8 and 9, respectively (patent WO2019212990A1, example 2)[1].
Related Catalog	Signaling Pathways >> PI3K/Akt/mTOR >> mTOR Research Areas >> Cancer
References	[1]. Jennifer PITZEN, et al. C40-, c28-, and c-32-linked rapamycin analogs as mtor inhibitors. WO2019212990A1.

Molecular Formula	C₉₃H₁₃₄N₁₀O₂₄
Molecular Weight	1776.11