(32-Carbonyl)-RMC-5552

Modify Date: 2024-01-11 21:39:24

(32-Carbonyl)-RMC-5552 Structure
(32-Carbonyl)-RMC-5552 structure
Common Name (32-Carbonyl)-RMC-5552
CAS Number 2382768-55-8 Molecular Weight 1776.11
Density N/A Boiling Point N/A
Molecular Formula C93H134N10O24 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (32-Carbonyl)-RMC-5552


(32-Carbonyl)-RMC-5552 is a potent mTOR inhibitor. (32-Carbonyl)-RMC-5552 inhibits mTORC1 and mTORC2 substrate (p-P70S6K-(T389), p-4E-BP1-(T37/36), AND p-AKT1/2/3-(S473)) phosphorylation with pIC50s of > 9, >9 and between 8 and 9, respectively (patent WO2019212990A1, example 2)[1].

 Names

Name (32-Carbonyl)-RMC-5552

 (32-Carbonyl)-RMC-5552 Biological Activity

Description (32-Carbonyl)-RMC-5552 is a potent mTOR inhibitor. (32-Carbonyl)-RMC-5552 inhibits mTORC1 and mTORC2 substrate (p-P70S6K-(T389), p-4E-BP1-(T37/36), AND p-AKT1/2/3-(S473)) phosphorylation with pIC50s of > 9, >9 and between 8 and 9, respectively (patent WO2019212990A1, example 2)[1].
Related Catalog
References

[1]. Jennifer PITZEN, et al. C40-, c28-, and c-32-linked rapamycin analogs as mtor inhibitors. WO2019212990A1.

 Chemical & Physical Properties

Molecular Formula C93H134N10O24
Molecular Weight 1776.11