Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Dirocaftor
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: Dirocaftor
Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
Purity: 98.0%
Stocking Period: 1 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

2137932-23-9

2137932-23-9 structure

2137932-23-9 structure

Name: Dirocaftor
Chemical Name: Dirocaftor
CAS Number: 2137932-23-9
Molecular Formula: C₂₂H₂₈N₂O₃Si₂
Molecular Weight: 424.64
Catalog: Signaling Pathways Membrane Transporter/Ion Channel CFTR
Create Date: 2021-12-20 10:18:01
Modify Date: 2025-08-22 14:50:56
Dirocaftor (PTI-808) is a CFTR potentiator that enhances the function of CFTR protein by opening chloride channels. Dirocaftor can be used for cystic fibrosis (CF) research[1][2].

Name	Dirocaftor

Description	Dirocaftor (PTI-808) is a CFTR potentiator that enhances the function of CFTR protein by opening chloride channels. Dirocaftor can be used for cystic fibrosis (CF) research[1][2].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> CFTR Research Areas >> Inflammation/Immunology
In Vitro	When combined with Nesolicaftor and Posenacaftor, Dirocaftor can restore CFTR function to nearly normal levels[2].
References	[1]. James A Reihill, et al. Modulation of Ion Transport to Restore Airway Hydration in Cystic Fibrosis. Genes (Basel). 2021 Mar 22;12(3):453. [2]. P. van Mourik, et al. WS10 Moving beyond body mass index to assess nutritional status in CF. Journal of Cystic Fibrosis 19S2 (2020) S1-S36.

Molecular Formula	C₂₂H₂₈N₂O₃Si₂
Molecular Weight	424.64

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