Shanghai Nianxing Industrial Co., Ltd
China
Product Name: JH-XVI-178
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: JH-XVI-178
Price: $Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
Purity: 98.0%
Stocking Period: 1 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

2648453-53-4

2648453-53-4 structure

2648453-53-4 structure

Name: JH-XVI-178
Chemical Name: JH-XVI-178
CAS Number: 2648453-53-4
Molecular Formula: C₂₂H₂₂ClN₇O
Molecular Weight: 435.91
Catalog: Signaling Pathways Cell Cycle/DNA Damage CDK
Create Date: 2021-12-23 14:20:35
Modify Date: 2025-08-28 18:36:08
JH-XVI-178 is a highly potent and selective inhibitor of CDK8/19 that displays low clearance and moderate oral pharmacokinetic properties.

Name	JH-XVI-178

Description	JH-XVI-178 is a highly potent and selective inhibitor of CDK8/19 that displays low clearance and moderate oral pharmacokinetic properties.
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> CDK
Target	CDK8:1 nM (IC50) CDK19:2 nM (IC50)
References	[1]. Hatcher JM, et al. Development of Highly Potent and Selective Pyrazolopyridine Inhibitor of CDK8/19. ACS Med Chem Lett. 2021 Oct 22;12(11):1689-1693.

Molecular Formula	C₂₂H₂₂ClN₇O
Molecular Weight	435.91

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