JH-XVI-178
Modify Date: 2025-08-28 18:36:08
JH-XVI-178 structure
|
Common Name | JH-XVI-178 | ||
|---|---|---|---|---|
| CAS Number | 2648453-53-4 | Molecular Weight | 435.91 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C22H22ClN7O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of JH-XVI-178JH-XVI-178 is a highly potent and selective inhibitor of CDK8/19 that displays low clearance and moderate oral pharmacokinetic properties. |
| Name | JH-XVI-178 |
|---|
| Description | JH-XVI-178 is a highly potent and selective inhibitor of CDK8/19 that displays low clearance and moderate oral pharmacokinetic properties. |
|---|---|
| Related Catalog | |
| Target |
CDK8:1 nM (IC50) CDK19:2 nM (IC50) |
| References |
| Molecular Formula | C22H22ClN7O |
|---|---|
| Molecular Weight | 435.91 |
| InChIKey | YLJSAFSDGFNKAC-UHFFFAOYSA-N |
| SMILES | Cn1ncc2cc(-c3cnc4n[nH]c(Cl)c4c3N3CCC4(CCNC4=O)CC3)ccc21 |