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2095484-82-3

2095484-82-3 structure
2095484-82-3 structure
  • Name: (R)-eIF4A3-IN-2
  • Chemical Name: (R)-eIF4A3-IN-2
  • CAS Number: 2095484-82-3
  • Molecular Formula: C25H19Br2ClN4O2
  • Molecular Weight: 602.70
  • Catalog: Research Areas Others
  • Create Date: 2022-01-22 18:36:29
  • Modify Date: 2024-01-16 23:16:33
  • (R)-eIF4A3-IN-2 is a less active enantiomer of eIF4A3-IN-2. eIF4A3-IN-2 is a highly selective and noncompetitive eukaryotic initiation factor 4A-3 (eIF4A3) inhibitor with an IC50 of 110 nM[1].

Name (R)-eIF4A3-IN-2
Description (R)-eIF4A3-IN-2 is a less active enantiomer of eIF4A3-IN-2. eIF4A3-IN-2 is a highly selective and noncompetitive eukaryotic initiation factor 4A-3 (eIF4A3) inhibitor with an IC50 of 110 nM[1].
Related Catalog
In Vitro Eukaryotic initiation factor 4A-3 (eIF4A3) is an Asp-Glu-Ala-Asp (DEAD) box-family adenosine triphosphate (ATP)-dependent RNA helicase[1].
References

[1]. Iwatani-Yoshihara M, et al. Discovery and Characterization of a Eukaryotic Initiation Factor 4A-3-Selective Inhibitor That Suppresses Nonsense-Mediated mRNA Decay. ACS Chem Biol. 2017;12(7):1760-1768.

Molecular Formula C25H19Br2ClN4O2
Molecular Weight 602.70