- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Di-tert-butyl iminodiacetate
- Price: ￥176.0/250mg ￥1466.0/5g ￥426.0/1g ￥2496.0/10g
- Purity: 95.0%
- Stocking Period: 2 Day
- Contact: Liu jia
- DC Chemicals Limited
- China
- Product Name: NH-bis(C1-Boc)
- Price:
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: di-tert-Butyl iminodiacetate
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
85916-13-8
85916-13-8 structure
- Name: Di-tert-butyl iminodiacetate
- Chemical Name: tert-butyl 2-[[2-[(2-methylpropan-2-yl)oxy]-2-oxoethyl]amino]acetate
- CAS Number: 85916-13-8
- Molecular Formula: C12H23NO4
- Molecular Weight: 245.315
- Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
- Create Date: 2018-04-13 08:00:00
- Modify Date: 2024-01-08 14:02:16
-
NH-bis(C1-Boc)is a uncleavable linker used for antibody-drug conjugates (ADC).
| Name | tert-butyl 2-[[2-[(2-methylpropan-2-yl)oxy]-2-oxoethyl]amino]acetate |
|---|---|
| Synonyms |
MFCD01863672
nitrilodiacetic acid di-tert-butyl ester (tert-butoxycarbonylmethyl-amino)-acetic acid tert-butyl ester Bis(2-methyl-2-propanyl) 2,2'-iminodiacetate aminodiacetic acid di-tert-butyl ester Di-tert-butyl iminodiacetate di-tert-butyl 2,2'-iminodiacetate HN(CH2CO2-tBu)2 iminodiacetic acid di-tert-butyl ester Glycine, N-[2-(1,1-dimethylethoxy)-2-oxoethyl]-, 1,1-dimethylethyl ester Di-tert-butyl iminodiacetate |
| Description | NH-bis(C1-Boc)is a uncleavable linker used for antibody-drug conjugates (ADC). |
|---|---|
| Related Catalog | |
| Target |
Noncleavable |
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 298.0±25.0 °C at 760 mmHg |
| Melting Point | 38-42ºC(lit.) |
| Molecular Formula | C12H23NO4 |
| Molecular Weight | 245.315 |
| Flash Point | 134.0±23.2 °C |
| Exact Mass | 245.162704 |
| PSA | 64.63000 |
| LogP | 2.72 |
| Vapour Pressure | 0.0±0.6 mmHg at 25°C |
| Index of Refraction | 1.446 |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi |
| Risk Phrases | 36/37/38 |
| Safety Phrases | 26-36/37/39 |
| RIDADR | NONH for all modes of transport |
|
~95%
85916-13-8 |
| Literature: Journal of Organic Chemistry, , vol. 68, # 10 p. 3999 - 4007 |
|
~%
85916-13-8 |
| Literature: EP369391 A3, ; |
|
~33%
85916-13-8 |
| Literature: US2012/149632 A1, ; |
|
~%
85916-13-8 |
| Literature: Journal of Organic Chemistry, , vol. 68, # 10 p. 3999 - 4007 |
|
~52%
85916-13-8 |
| Literature: Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, , vol. 42, # 6 p. 373 - 377 |
|
~37%
85916-13-8 |
| Literature: Tetrahedron Letters, , vol. 33, # 42 p. 6303 - 6306 |
| Precursor 7 | |
|---|---|
| DownStream 0 | |