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153049-05-9

153049-05-9 structure
153049-05-9 structure
  • Name: KSPWFTTL
  • Chemical Name: KSPWFTTL
  • CAS Number: 153049-05-9
  • Molecular Formula: C48H70N10O12
  • Molecular Weight: 979.13
  • Catalog: Research Areas Cancer
  • Create Date: 2022-03-08 22:37:39
  • Modify Date: 2025-08-25 12:27:15
  • KSPWFTTL is an immunodominant Kb-restricted epitope from the p15E transmembrane protein. KSPWFTTL can restore susceptibility of a tumor line to anti-AKR/Gross MuLV cytotoxic T lymphocytes[1][2].

Name KSPWFTTL
Description KSPWFTTL is an immunodominant Kb-restricted epitope from the p15E transmembrane protein. KSPWFTTL can restore susceptibility of a tumor line to anti-AKR/Gross MuLV cytotoxic T lymphocytes[1][2].
Related Catalog
In Vitro KSPWFTTL is derived from the retroviral p15 TM envelope protein. The cytolytic T-lymphocyte (CTL)-insusceptible, variant cl.18-5 clonal line, after pulsed with the KSPWFTTL peptide, becomes susceptible to lysis by antiviral CTL[2].
References

[1]. White HD, et, al. An immunodominant Kb-restricted peptide from the p15E transmembrane protein of endogenous ecotropic murine leukemia virus (MuLV) AKR623 that restores susceptibility of a tumor line to anti-AKR/Gross MuLV cytotoxic T lymphocytes. J Virol. 1994 Feb;68(2):897-904.

[2]. Rich RF, et, al. Antiretroviral cytolytic T-lymphocyte nonresponsiveness: FasL/Fas-mediated inhibition of CD4(+) and CD8(+) antiviral T cells by viral antigen-positive veto cells. J Virol. 1999 May;73(5):3826-34.

Molecular Formula C48H70N10O12
Molecular Weight 979.13
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