1076225-26-7

1076225-26-7 structure

Name: (rac)-PF-998425
Chemical Name: (rac)-PF-998425
CAS Number: 1076225-26-7
Molecular Formula: C₁₄H₁₄F₃NO
Molecular Weight: 269.26
Catalog: Research Areas Endocrinology
Create Date: 2022-02-20 15:42:25
Modify Date: 2024-01-19 21:10:43
(rac)-PF-998425 is a potent, selective, nonsteroidal androgen receptor (AR) antagonist. (rac)-PF-998425 has IC50 values of 26 and 90 nM in the AR binding and cellular assays, respectively. (rac)-PF-998425 has the potential for the research of the androgenetic alopecia[1].

Name	(rac)-PF-998425

Description	(rac)-PF-998425 is a potent, selective, nonsteroidal androgen receptor (AR) antagonist. (rac)-PF-998425 has IC50 values of 26 and 90 nM in the AR binding and cellular assays, respectively. (rac)-PF-998425 has the potential for the research of the androgenetic alopecia[1].
Related Catalog	Research Areas >> Endocrinology Signaling Pathways >> Others >> Androgen Receptor
References	[1]. Li JJ, et al. Rational design and synthesis of 4-((1R,2R)-2-hydroxycyclohexyl)-2(trifluoromethyl)benzonitrile (PF-998425), a novel, nonsteroidal androgen receptor antagonist devoid of phototoxicity for dermatological indications. J Med Chem. 2008;51(21):7010-7014.

Molecular Formula	C₁₄H₁₄F₃NO
Molecular Weight	269.26