1331889-36-1

1331889-36-1 structure

Name: L-Norleucine-d9
Chemical Name: L-Norleucine-d9
CAS Number: 1331889-36-1
Molecular Formula: C₆H₄D₉NO₂
Molecular Weight: 140.23
Catalog: Signaling Pathways Anti-infection Influenza Virus
Create Date: 2022-04-01 17:48:50
Modify Date: 2024-01-20 11:01:51
L-Norleucine-d9 ((S)-2-Aminohexanoic acid-d9) is the deuterium labeled L-Norleucine. L-Norleucine ((S)-2-Aminohexanoic acid) is an isomer of leucine, specifically affects protein synthesis in skeletal muscle, and has antivirus activity.

Name	L-Norleucine-d9
Synonyms	L-(3,3,4,4,5,5,6,6,6-2H9)Norleucine (S)-2-Aminohexanoic Acid-d9 L-Norleucine-3,3,4,4,5,5,6,6,6-d9

Description	L-Norleucine-d9 ((S)-2-Aminohexanoic acid-d9) is the deuterium labeled L-Norleucine. L-Norleucine ((S)-2-Aminohexanoic acid) is an isomer of leucine, specifically affects protein synthesis in skeletal muscle, and has antivirus activity.
Related Catalog	Signaling Pathways >> Anti-infection >> Influenza Virus Research Areas >> Cancer Research Areas >> Infection
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Schott KJ, et al. On the role of branched-chain amino acids in protein turnover of skeletal muscle. Studies in vivo with L-norleucine. Z Naturforsch C. 1985 May-Jun;40(5-6):427-37. [3]. He T, et al. The homeostasis-maintaining metabolites from bacterial stress response to bacteriophage infection suppress tumor metastasis. Oncogene. 2018 Jun 20.