1795136-36-5

1795136-36-5 structure

Name: Aldicarb sulfoxide-d3
Chemical Name: Aldicarb-d3 Sulfoxide
CAS Number: 1795136-36-5
Molecular Formula: C₇H₁₁D₃N₂O₃S
Molecular Weight: 209.28
Catalog: Research Areas Metabolic Disease
Create Date: 2022-03-28 16:50:51
Modify Date: 2024-01-24 23:01:48
Aldicarb sulfoxide-d3 is the deuterium labled Aldicarb sulfoxide (HY-124104). Aldicarb sulfoxide is a metabolite of Aldicarb. Aldicarb sulfoxide affects the glutathione-linked enzymes in CHO-K1 cells. Aldicarb sulfoxide inhibits cholinesterase (ChE) and carboxylesterase (CaE) with IC50 of 10 μM for both in zebrafish[1][2].

Name	Aldicarb-d3 Sulfoxide
Synonyms	Propanal, 2-methyl-2-(methylsulfinyl)-, O-[(methyl-d3-amino)carbonyl]oxime, (1E)- (5E)-7,7-Dimethyl(1,1,1-2H3)-4-oxa-8-thia-2,5-diazanon-5-en-3-one 8-oxide 2-Methyl-2-(methylsulfinyl)propanal O-[(Methylamino-d3)carbonyl]oxime 2-Methyl-2-(methylsulfinyl)propionaldehyde O-(Methylcarbamoyl-d3)oxime

Description	Aldicarb sulfoxide-d3 is the deuterium labled Aldicarb sulfoxide (HY-124104). Aldicarb sulfoxide is a metabolite of Aldicarb. Aldicarb sulfoxide affects the glutathione-linked enzymes in CHO-K1 cells. Aldicarb sulfoxide inhibits cholinesterase (ChE) and carboxylesterase (CaE) with IC50 of 10 μM for both in zebrafish[1][2].
Related Catalog	Research Areas >> Metabolic Disease
References	[1]. Maran E, et al. Effects of four carbamate compounds on antioxidant parameters. Ecotoxicol Environ Saf. 2009 Mar;72(3):922-30. [2]. Küster E, Altenburger R. Suborganismic and organismic effects of aldicarb and its metabolite aldicarb-sulfoxide to the zebrafish embryo (Danio rerio). Chemosphere. 2007 Jun;68(4):751-60. [3]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.