1551459-37-0

1551459-37-0 structure

1551459-37-0 structure

Name: FXIa-IN-6
Chemical Name: FXIa-IN-6
CAS Number: 1551459-37-0
Molecular Formula: C₃₁H₂₉ClF₂N₄O₄
Molecular Weight: 595.04
Catalog: Signaling Pathways Metabolic Enzyme/Protease Factor Xa
Create Date: 2022-03-24 16:17:45
Modify Date: 2024-01-14 11:13:32
FXIa-IN-6 is a potent FXIa inhibitor with selectivity against most of the relevant serine proteases (Ki = 0.3 nM).

Name	FXIa-IN-6

Description	FXIa-IN-6 is a potent FXIa inhibitor with selectivity against most of the relevant serine proteases (Ki = 0.3 nM).
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Metabolic Enzyme/Protease >> Factor Xa
References	[1]. Yang W, et al. Discovery of a High Affinity, Orally Bioavailable Macrocyclic FXIa Inhibitor with Antithrombotic Activity in Preclinical Species. J Med Chem. 2020 Jul 9;63(13):7226-7242.

Molecular Formula	C₃₁H₂₉ClF₂N₄O₄
Molecular Weight	595.04