2439058-23-6

2439058-23-6 structure

Name: HDAC6 degrader-1
Chemical Name: HDAC6 degrader-1
CAS Number: 2439058-23-6
Molecular Formula: C₄₀H₄₅N₉O₉
Molecular Weight: 795.84
Catalog: Signaling Pathways PROTAC PROTAC
Create Date: 2022-07-26 17:50:15
Modify Date: 2024-01-14 20:24:15
HDAC6 degrader-1 is a PROTAC that comprises a selective HDAC6 inhibitor Nexturastat A (Nex A) as the HDAC6 binder, a linker and a ligand for recruiting E3 ligase. HDAC6 degrader-1 induces significant degradation of HDAC6, exhibits excellent selectivity against other HDACs, and demonstrates efficient inhibition of cell proliferation[1].

Name	HDAC6 degrader-1

Description	HDAC6 degrader-1 is a PROTAC that comprises a selective HDAC6 inhibitor Nexturastat A (Nex A) as the HDAC6 binder, a linker and a ligand for recruiting E3 ligase. HDAC6 degrader-1 induces significant degradation of HDAC6, exhibits excellent selectivity against other HDACs, and demonstrates efficient inhibition of cell proliferation[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> PROTAC >> PROTAC
References	[1]. An Z, et al. Developing potent PROTACs tools for selective degradation of HDAC6 protein [published correction appears in Protein Cell. 2019 Feb 22;:]. Protein Cell. 2019;10(8):606-609.

Molecular Formula	C₄₀H₄₅N₉O₉
Molecular Weight	795.84