HDAC6 degrader-1
Modify Date: 2025-11-24 16:52:10
HDAC6 degrader-1 structure
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Common Name | HDAC6 degrader-1 | ||
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| CAS Number | 2439058-23-6 | Molecular Weight | 795.84 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C40H45N9O9 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of HDAC6 degrader-1HDAC6 degrader-1 is a PROTAC that comprises a selective HDAC6 inhibitor Nexturastat A (Nex A) as the HDAC6 binder, a linker and a ligand for recruiting E3 ligase. HDAC6 degrader-1 induces significant degradation of HDAC6, exhibits excellent selectivity against other HDACs, and demonstrates efficient inhibition of cell proliferation[1]. |
| Name | HDAC6 degrader-1 |
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| Description | HDAC6 degrader-1 is a PROTAC that comprises a selective HDAC6 inhibitor Nexturastat A (Nex A) as the HDAC6 binder, a linker and a ligand for recruiting E3 ligase. HDAC6 degrader-1 induces significant degradation of HDAC6, exhibits excellent selectivity against other HDACs, and demonstrates efficient inhibition of cell proliferation[1]. |
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| Related Catalog | |
| References |
| Molecular Formula | C40H45N9O9 |
|---|---|
| Molecular Weight | 795.84 |
| InChIKey | NLVMRCQAKUCFIA-UHFFFAOYSA-N |
| SMILES | O=C1CCC(N2C(=O)c3cccc(NCCOCCOCCn4cc(CCCCN(Cc5ccc(C(=O)NO)cc5)C(=O)Nc5ccccc5)nn4)c3C2=O)C(=O)N1 |