2296718-09-5

2296718-09-5 structure
2296718-09-5 structure
  • Name: SHP2 inhibitor LY6
  • Chemical Name: SHP2 inhibitor LY6
  • CAS Number: 2296718-09-5
  • Molecular Formula: C30H27Cl2N3O4
  • Molecular Weight: 564.46
  • Catalog: Signaling Pathways Metabolic Enzyme/Protease Phosphatase
  • Create Date: 2022-07-01 15:10:44
  • Modify Date: 2024-01-14 11:28:17
  • SHP2 inhibitor LY6 (LY6) is potent and selective inhibitor of SHP2, with an IC50 of 9.8 µM. SHP2 inhibitor LY6 can inhibits SHP2-mediated cell signaling and proliferation[1].

Name SHP2 inhibitor LY6
Description SHP2 inhibitor LY6 (LY6) is potent and selective inhibitor of SHP2, with an IC50 of 9.8 µM. SHP2 inhibitor LY6 can inhibits SHP2-mediated cell signaling and proliferation[1].
Related Catalog
Target

IC50: 9.8 µM (SHP2)[1]

References

[1]. Wu X, et, al. Small Molecule Inhibitor that Stabilizes the Autoinhibited Conformation of the Oncogenic Tyrosine Phosphatase SHP2. J Med Chem. 2019 Feb 14;62(3):1125-1137.

Molecular Formula C30H27Cl2N3O4
Molecular Weight 564.46
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