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2677709-81-6

2677709-81-6 structure
2677709-81-6 structure
  • Name: FGFR2-IN-2
  • Chemical Name: FGFR2-IN-2
  • CAS Number: 2677709-81-6
  • Molecular Formula: C23H22N4O
  • Molecular Weight: 370.45
  • Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK FGFR
  • Create Date: 2022-04-07 18:47:09
  • Modify Date: 2024-01-02 15:40:41
  • FGFR2-IN-2 (Compound 38) is a selective FGFR2 inhibitor with IC50s of 389, 29, and 758 nM for FGFR1, FGFR2, and FGFR3, respectively[1].

Name FGFR2-IN-2
Description FGFR2-IN-2 (Compound 38) is a selective FGFR2 inhibitor with IC50s of 389, 29, and 758 nM for FGFR1, FGFR2, and FGFR3, respectively[1].
Related Catalog
Target

FGFR2:29 nM (IC50)

FGFR1:389 nM (IC50)

FGFR3:758 nM (IC50)

References

[1]. Lewis D Turner, et al. From Fragment to Lead: De Novo Design and Development toward a Selective FGFR2 Inhibitor. J Med Chem. 2022 Jan 27;65(2):1481-1504.

Molecular Formula C23H22N4O
Molecular Weight 370.45