FGFR2-IN-2

Modify Date: 2024-01-02 15:40:41

FGFR2-IN-2 Structure
FGFR2-IN-2 structure
Common Name FGFR2-IN-2
CAS Number 2677709-81-6 Molecular Weight 370.45
Density N/A Boiling Point N/A
Molecular Formula C23H22N4O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of FGFR2-IN-2


FGFR2-IN-2 (Compound 38) is a selective FGFR2 inhibitor with IC50s of 389, 29, and 758 nM for FGFR1, FGFR2, and FGFR3, respectively[1].

 Names

Name FGFR2-IN-2

 FGFR2-IN-2 Biological Activity

Description FGFR2-IN-2 (Compound 38) is a selective FGFR2 inhibitor with IC50s of 389, 29, and 758 nM for FGFR1, FGFR2, and FGFR3, respectively[1].
Related Catalog
Target

FGFR2:29 nM (IC50)

FGFR1:389 nM (IC50)

FGFR3:758 nM (IC50)

References

[1]. Lewis D Turner, et al. From Fragment to Lead: De Novo Design and Development toward a Selective FGFR2 Inhibitor. J Med Chem. 2022 Jan 27;65(2):1481-1504.

 Chemical & Physical Properties

Molecular Formula C23H22N4O
Molecular Weight 370.45