2201098-03-3

2201098-03-3 structure

Name: HPK1-IN-15
Chemical Name: HPK1-IN-15
CAS Number: 2201098-03-3
Molecular Formula: C₂₄H₂₁ClF₃N₅
Molecular Weight: 471.91
Catalog: Signaling Pathways MAPK/ERK Pathway MAP4K
Create Date: 2022-04-07 07:54:56
Modify Date: 2025-08-23 13:27:34
HPK1-IN-15 is a potent and selective inhibitor of HPK1. Hematopoietic progenitor kinase 1 (HPKl) originally cloned from hematopoietic progenitor cells is a member of MAP kinase kinase kinase kinases (MAP4Ks) family. HPK1-IN-15 is useful in researching, preventing or ameliorating diseases or disorders associated with HPK1 activity such as cancer (extracted from patent WO2018049200A1, compound 50)[1].

Name	HPK1-IN-15

Description	HPK1-IN-15 is a potent and selective inhibitor of HPK1. Hematopoietic progenitor kinase 1 (HPKl) originally cloned from hematopoietic progenitor cells is a member of MAP kinase kinase kinase kinases (MAP4Ks) family. HPK1-IN-15 is useful in researching, preventing or ameliorating diseases or disorders associated with HPK1 activity such as cancer (extracted from patent WO2018049200A1, compound 50)[1].
Related Catalog	Signaling Pathways >> MAPK/ERK Pathway >> MAP4K Research Areas >> Cancer Research Areas >> Inflammation/Immunology
References	[1]. Hai-Fen Ye, et al. Pyrazolopyridine derivatives as hpk1 modulators and uses thereof for the treatment of cancer. Patent WO2018049200A1.

Molecular Formula	C₂₄H₂₁ClF₃N₅
Molecular Weight	471.91