Name | Cas9-IN-2 |
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Description | Cas9-IN-2 is a potent Cas9 inhibitor (IC50=246 μM), Cas9-IN-2 acts by binding to apo-Cas9 to prevent Cas9:gRNA complex formation, which can potentially be applied to modulate and control Cas9 activity in various applications[1]. |
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Related Catalog | |
In Vitro | Cas9-IN-1 (compound 2) (200 and 500 μM; overnight) helps the E. coli selection strain to survive SpyCas9-induced killing[1]. |
References |
Molecular Formula | C21H27N5O4S2 |
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Molecular Weight | 477.60 |