Cas9-IN-2

Modify Date: 2024-01-08 11:23:29

Cas9-IN-2 structure	Common Name	Cas9-IN-2
	CAS Number	1030133-34-6	Molecular Weight	477.60
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₁H₂₇N₅O₄S₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Cas9-IN-2

Cas9-IN-2 is a potent Cas9 inhibitor (IC50=246 μM), Cas9-IN-2 acts by binding to apo-Cas9 to prevent Cas9:gRNA complex formation, which can potentially be applied to modulate and control Cas9 activity in various applications[1].

Name	Cas9-IN-2

Description	Cas9-IN-2 is a potent Cas9 inhibitor (IC50=246 μM), Cas9-IN-2 acts by binding to apo-Cas9 to prevent Cas9:gRNA complex formation, which can potentially be applied to modulate and control Cas9 activity in various applications[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Cell Cycle/DNA Damage >> CRISPR/Cas9
In Vitro	Cas9-IN-1 (compound 2) (200 and 500 μM; overnight) helps the E. coli selection strain to survive SpyCas9-induced killing[1].
References	[1]. Lee SW, et al. Identification and Optimization of Novel Small-Molecule Cas9 Inhibitors by Cell-Based High-Throughput Screening. J Med Chem. 2022;65(4):3266-3305.

Molecular Formula	C₂₁H₂₇N₅O₄S₂
Molecular Weight	477.60

DC Chemicals Limited
China
Product Name: Cas9-IN-2
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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