2749555-66-4

2749555-66-4 structure

Name: DX3-213B
Chemical Name: DX3-213B
CAS Number: 2749555-66-4
Molecular Formula: C₂₀H₂₈F₂N₂O₅S₂
Molecular Weight: 478.57
Create Date: 2022-05-05 17:34:45
Modify Date: 2024-04-06 15:46:52
DX3-213B is a highly potent, orally active oxidative phosphorylation (OXPHOS) complex I inhibitor (IC50=3.6 nM). DX3-213B impairs ATP generation (IC50=11 nM), and blocks MIA PaCa-2 cell growth (GI50=11 nM). DX3-213B is used for the research of the pancreatic cancer[1].

Name	DX3-213B

Description	DX3-213B is a highly potent, orally active oxidative phosphorylation (OXPHOS) complex I inhibitor (IC50=3.6 nM). DX3-213B impairs ATP generation (IC50=11 nM), and blocks MIA PaCa-2 cell growth (GI50=11 nM). DX3-213B is used for the research of the pancreatic cancer[1].
Related Catalog	Research Areas >> Cancer
References	[1]. Xue D, et al. Multiparameter Optimization of Oxidative Phosphorylation Inhibitors for the Treatment of Pancreatic Cancer. J Med Chem. 2022;65(4):3404-3419.

Molecular Formula	C₂₀H₂₈F₂N₂O₅S₂
Molecular Weight	478.57