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2495750-19-9

2495750-19-9 structure
2495750-19-9 structure
  • Name: LC kinetic stabilizer-1
  • Chemical Name: LC kinetic stabilizer-1
  • CAS Number: 2495750-19-9
  • Molecular Formula: C27H31N5O3
  • Molecular Weight: 473.57
  • Create Date: 2022-06-22 18:43:41
  • Modify Date: 2024-01-12 17:32:34
  • LC kinetic stabilizer-1 (compound 21) is a potent and selective amyloidogenic immunoglobulin light chain kinetic stabilizer with EC50s of 140 and 74.1 nM for WIL-FL* and WIL-FL* T46L/F49Y, respectively. WIL-FL is an amyloidogenic FL LC dimer[1].
Name LC kinetic stabilizer-1
Description LC kinetic stabilizer-1 (compound 21) is a potent and selective amyloidogenic immunoglobulin light chain kinetic stabilizer with EC50s of 140 and 74.1 nM for WIL-FL* and WIL-FL* T46L/F49Y, respectively. WIL-FL is an amyloidogenic FL LC dimer[1].
Related Catalog
References

[1]. Yan NL, et al. Amyloidogenic immunoglobulin light chain kinetic stabilizers comprising a simple urea linker module reveal a novel binding sub-site. Bioorg Med Chem Lett. 2022;60:128571.

Molecular Formula C27H31N5O3
Molecular Weight 473.57
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title: CAS No. 2495750-19-9 | Chemsrc address: https://m.chemsrc.com/en/baike/1705426.html

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