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  • BioBioPha
  • China
  • Product Name: Thalidezine
  • Price: ¥4150.0/5mg
  • Purity: 97.0%
  • Stocking Period: 10 Day
  • Contact: Xueping-Zheng

18251-36-0

18251-36-0 structure
18251-36-0 structure
  • Name: Thalidezine
  • Chemical Name: thalidezine
  • CAS Number: 18251-36-0
  • Molecular Formula: C38H42N2O7
  • Molecular Weight: 638.74900
  • Catalog: Research Areas Cancer
  • Create Date: 2016-11-07 10:54:43
  • Modify Date: 2024-01-02 07:30:32
  • Thalidezine is a novel activator of AMP-activated protein kinase (AMPK). Thalidezine can eliminate anti-apoptotic cancer cells through energy-mediated autophagy death. Thalidezine can be used to study apoptosis intervention [1].

Name thalidezine
Synonyms O5-demethyl-hernandezine
5-hydroxy-tetrandrine
Hydroxytetrandrin
(+)-thalidezine
Description Thalidezine is a novel activator of AMP-activated protein kinase (AMPK). Thalidezine can eliminate anti-apoptotic cancer cells through energy-mediated autophagy death. Thalidezine can be used to study apoptosis intervention [1].
Related Catalog
References

[1]. Law BYK, et al. Thalidezine, a novel AMPK activator, eliminates apoptosis-resistant cancer cells through energy-mediated autophagic cell death. Oncotarget. 2017 May 2;8(18):30077-30091.  

Density 1.206g/cm3
Boiling Point 735ºC at 760mmHg
Molecular Formula C38H42N2O7
Molecular Weight 638.74900
Flash Point 398.3ºC
Exact Mass 638.29900
PSA 82.09000
LogP 6.74380
Vapour Pressure 2.49E-22mmHg at 25°C
Index of Refraction 1.595

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18251-36-0 structure

18251-36-0

Literature: Wiriyachitra; Cava Journal of Organic Chemistry, 1977 , vol. 42, # 13 p. 2274 - 2277

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18251-36-0 structure

18251-36-0

Literature: Wiriyachitra; Cava Journal of Organic Chemistry, 1977 , vol. 42, # 13 p. 2274 - 2277
Precursor  2

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