Thalidezine

Modify Date: 2024-01-02 07:30:32

Thalidezine Structure
Thalidezine structure
Common Name Thalidezine
CAS Number 18251-36-0 Molecular Weight 638.74900
Density 1.206g/cm3 Boiling Point 735ºC at 760mmHg
Molecular Formula C38H42N2O7 Melting Point N/A
MSDS N/A Flash Point 398.3ºC

 Use of Thalidezine


Thalidezine is a novel activator of AMP-activated protein kinase (AMPK). Thalidezine can eliminate anti-apoptotic cancer cells through energy-mediated autophagy death. Thalidezine can be used to study apoptosis intervention [1].

 Names

Name thalidezine
Synonym More Synonyms

 Thalidezine Biological Activity

Description Thalidezine is a novel activator of AMP-activated protein kinase (AMPK). Thalidezine can eliminate anti-apoptotic cancer cells through energy-mediated autophagy death. Thalidezine can be used to study apoptosis intervention [1].
Related Catalog
References

[1]. Law BYK, et al. Thalidezine, a novel AMPK activator, eliminates apoptosis-resistant cancer cells through energy-mediated autophagic cell death. Oncotarget. 2017 May 2;8(18):30077-30091.  

 Chemical & Physical Properties

Density 1.206g/cm3
Boiling Point 735ºC at 760mmHg
Molecular Formula C38H42N2O7
Molecular Weight 638.74900
Flash Point 398.3ºC
Exact Mass 638.29900
PSA 82.09000
LogP 6.74380
Vapour Pressure 2.49E-22mmHg at 25°C
Index of Refraction 1.595

 Synthetic Route

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Thalidezine Structure

Thalidezine

CAS#:18251-36-0

Literature: Wiriyachitra; Cava Journal of Organic Chemistry, 1977 , vol. 42, # 13 p. 2274 - 2277

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Thalidezine Structure

Thalidezine

CAS#:18251-36-0

Literature: Wiriyachitra; Cava Journal of Organic Chemistry, 1977 , vol. 42, # 13 p. 2274 - 2277

 Precursor & DownStream

Precursor  2

DownStream  0

 Synonyms

O5-demethyl-hernandezine
5-hydroxy-tetrandrine
Hydroxytetrandrin
(+)-thalidezine
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