2654026-13-6

2654026-13-6 structure
2654026-13-6 structure
  • Name: AKT-IN-8
  • Chemical Name: AKT-IN-8
  • CAS Number: 2654026-13-6
  • Molecular Formula: C22H25ClN6O3
  • Molecular Weight: 456.93
  • Catalog: Signaling Pathways PI3K/Akt/mTOR Akt
  • Create Date: 2022-06-30 14:43:09
  • Modify Date: 2024-08-09 16:31:27
  • AKT-IN-8 is a potent AKT inhibitor with IC50s of 4.46, 2.44, and 9.47 nM for AKT1, AKT2, and AKT3, respectively[1].

Name AKT-IN-8
Description AKT-IN-8 is a potent AKT inhibitor with IC50s of 4.46, 2.44, and 9.47 nM for AKT1, AKT2, and AKT3, respectively[1].
Related Catalog
Target

Akt1:4.46 nM (IC50)

Akt2:2.44 nM (IC50)

Akt3:9.47 nM (IC50)

References

[1]. Fused tetracyclic derivative, preparation method therefor, and medical use thereof. WO2021121276A1.

Molecular Formula C22H25ClN6O3
Molecular Weight 456.93