2642224-22-2

2642224-22-2 structure

2642224-22-2 structure

Name: Axl-IN-6
Chemical Name: Axl-IN-6
CAS Number: 2642224-22-2
Molecular Formula: C₃₂H₃₆N₄O
Molecular Weight: 492.65
Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK TAM Receptor
Create Date: 2022-05-30 12:04:53
Modify Date: 2024-01-02 21:27:54
Axl-IN-6 (compound 14) is an orally active and potent AXL inhibitor. Axl-IN-6 is well tolerated and significantly inhibits the tumor growth in MV-4-11 subcutaneous xenograft model[1].

Name	Axl-IN-6

Description	Axl-IN-6 (compound 14) is an orally active and potent AXL inhibitor. Axl-IN-6 is well tolerated and significantly inhibits the tumor growth in MV-4-11 subcutaneous xenograft model[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> TAM Receptor
Target	AXL[1]
References	[1]. Zhang LL, et al. Discovery a series of quinazolin derivatives as potent AXL inhibitors. Eur J Med Chem. 2022 Apr 6;237:114316.[published online ahead of print, 2022 Apr 6]. Eur J Med Chem. 2022;237:114316.

Molecular Formula	C₃₂H₃₆N₄O
Molecular Weight	492.65