2688098-02-2

2688098-02-2 structure

2688098-02-2 structure

Name: CDK4/6-IN-9
Chemical Name: CDK4/6-IN-9
CAS Number: 2688098-02-2
Molecular Formula: C₂₂H₂₃FN₈
Molecular Weight: 418.47
Catalog: Signaling Pathways Cell Cycle/DNA Damage CDK
Create Date: 2022-07-04 10:53:20
Modify Date: 2024-01-29 19:24:52
CDK4/6-IN-9 (compound 10) is a selective CDK4/6 inhibitor with an IC50 of 905 nM for CDK6/cyclin D1. CDK4/6-IN-9 has the potential for multiple myeloma (MM) research[1].

Name	CDK4/6-IN-9

Description	CDK4/6-IN-9 (compound 10) is a selective CDK4/6 inhibitor with an IC50 of 905 nM for CDK6/cyclin D1. CDK4/6-IN-9 has the potential for multiple myeloma (MM) research[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> CDK
Target	CDK6/cyclinD1:905 nM (IC50) CDK4/cyclinD1
References	[1]. Kai Yuan, et al. Discovery of novel and orally bioavailable CDK 4/6 inhibitors with high kinome selectivity, low toxicity and long-acting stability for the treatment of multiple myeloma. Eur J Med Chem. 2022 Jan 15;228:114024.

Molecular Formula	C₂₂H₂₃FN₈
Molecular Weight	418.47