2665665-09-6

2665665-09-6 structure
2665665-09-6 structure
  • Name: FGFR-IN-2
  • Chemical Name: FGFR-IN-2
  • CAS Number: 2665665-09-6
  • Molecular Formula: C25H30N6O2
  • Molecular Weight: 446.54
  • Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK FGFR
  • Create Date: 2022-05-30 17:32:26
  • Modify Date: 2023-01-13 15:45:56
  • FGFR-IN-2 (compound 1) is a potent FGFR inhibitor with IC50s of 7.3 nM, 4.3 nM, 7.6 nM, 11 nM for FGFR1, FGFR2, FGFR3 and FGFR4, respectively. FGFR-IN-2 has the potential for cancer research[1].

Name FGFR-IN-2
Description FGFR-IN-2 (compound 1) is a potent FGFR inhibitor with IC50s of 7.3 nM, 4.3 nM, 7.6 nM, 11 nM for FGFR1, FGFR2, FGFR3 and FGFR4, respectively. FGFR-IN-2 has the potential for cancer research[1].
Related Catalog
Target

FGFR1:7.3 nM (IC50)

FGFR2:4.3 nM (IC50)

FGFR3:7.6 nM (IC50)

FGFR4:11 nM (IC50)

References

[1]. Don Zhang, et al. Pyridazine and 1,2,4-triazine derivatives as fgfr kinase inhibitors. WO2021146163A1.

Molecular Formula C25H30N6O2
Molecular Weight 446.54