FGFR-IN-2

Modify Date: 2024-07-16 23:25:45

FGFR-IN-2 Structure
FGFR-IN-2 structure
Common Name FGFR-IN-2
CAS Number 2665665-09-6 Molecular Weight 446.54
Density N/A Boiling Point N/A
Molecular Formula C25H30N6O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of FGFR-IN-2


FGFR-IN-2 (compound 1) is a potent FGFR inhibitor with IC50s of 7.3 nM, 4.3 nM, 7.6 nM, 11 nM for FGFR1, FGFR2, FGFR3 and FGFR4, respectively. FGFR-IN-2 has the potential for cancer research[1].

 Names

Name FGFR-IN-2

 FGFR-IN-2 Biological Activity

Description FGFR-IN-2 (compound 1) is a potent FGFR inhibitor with IC50s of 7.3 nM, 4.3 nM, 7.6 nM, 11 nM for FGFR1, FGFR2, FGFR3 and FGFR4, respectively. FGFR-IN-2 has the potential for cancer research[1].
Related Catalog
Target

FGFR1:7.3 nM (IC50)

FGFR2:4.3 nM (IC50)

FGFR3:7.6 nM (IC50)

FGFR4:11 nM (IC50)

References

[1]. Don Zhang, et al. Pyridazine and 1,2,4-triazine derivatives as fgfr kinase inhibitors. WO2021146163A1.

 Chemical & Physical Properties

Molecular Formula C25H30N6O2
Molecular Weight 446.54
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