901654-94-2

901654-94-2 structure

Name: GPVI antagonist 3
Chemical Name: GPVI antagonist 3
CAS Number: 901654-94-2
Molecular Formula: C₂₂H₂₃N₃O₄
Molecular Weight: 393.44
Catalog: Research Areas Cardiovascular Disease
Create Date: 2022-05-30 17:45:11
Modify Date: 2024-01-03 08:00:16
GPVI antagonist 3 (Compound 2) is a potential antagonist of Glycoprotein VI (GPVI). IC50 values of GPVI antagonist 3 are, respectively, 1.01 μM for collagen, 1.92 μM for CRP, 7.24 μM for convulxin and 51.74 μM for thrombin. Glycoprotein VI (GPVI) is a platelet major collagen receptor and a target for potent and safe antithrombotic research. GPVI antagonist 3 is a promising antiplatelet agent[1].

Name	GPVI antagonist 3

Description	GPVI antagonist 3 (Compound 2) is a potential antagonist of Glycoprotein VI (GPVI). IC50 values of GPVI antagonist 3 are, respectively, 1.01 μM for collagen, 1.92 μM for CRP, 7.24 μM for convulxin and 51.74 μM for thrombin. Glycoprotein VI (GPVI) is a platelet major collagen receptor and a target for potent and safe antithrombotic research. GPVI antagonist 3 is a promising antiplatelet agent[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Others >> Others
References	[1]. Olğaç S, et al. Identification of novel antiplatelet agents by targeting Glycoprotein VI: A combined virtual screening study. Bioorg Chem. 2022;121:105661.

Molecular Formula	C₂₂H₂₃N₃O₄
Molecular Weight	393.44