GPVI antagonist 3

Modify Date: 2024-01-03 08:00:16

GPVI antagonist 3 Structure
GPVI antagonist 3 structure
Common Name GPVI antagonist 3
CAS Number 901654-94-2 Molecular Weight 393.44
Density N/A Boiling Point N/A
Molecular Formula C22H23N3O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of GPVI antagonist 3


GPVI antagonist 3 (Compound 2) is a potential antagonist of Glycoprotein VI (GPVI). IC50 values of GPVI antagonist 3 are, respectively, 1.01 μM for collagen, 1.92 μM for CRP, 7.24 μM for convulxin and 51.74 μM for thrombin. Glycoprotein VI (GPVI) is a platelet major collagen receptor and a target for potent and safe antithrombotic research. GPVI antagonist 3 is a promising antiplatelet agent[1].

 Names

Name GPVI antagonist 3

 GPVI antagonist 3 Biological Activity

Description GPVI antagonist 3 (Compound 2) is a potential antagonist of Glycoprotein VI (GPVI). IC50 values of GPVI antagonist 3 are, respectively, 1.01 μM for collagen, 1.92 μM for CRP, 7.24 μM for convulxin and 51.74 μM for thrombin. Glycoprotein VI (GPVI) is a platelet major collagen receptor and a target for potent and safe antithrombotic research. GPVI antagonist 3 is a promising antiplatelet agent[1].
Related Catalog
References

[1]. Olğaç S, et al. Identification of novel antiplatelet agents by targeting Glycoprotein VI: A combined virtual screening study. Bioorg Chem. 2022;121:105661.

 Chemical & Physical Properties

Molecular Formula C22H23N3O4
Molecular Weight 393.44