2170606-94-5

2170606-94-5 structure

Name: MAK683 hydrochloride
Chemical Name: MAK683 hydrochloride
CAS Number: 2170606-94-5
Molecular Formula: C₂₀H₁₈ClFN₆O
Molecular Weight: 412.85
Catalog: Signaling Pathways Epigenetics Histone Methyltransferase
Create Date: 2022-05-22 18:16:09
Modify Date: 2024-01-03 12:10:33
MAK683 hydrochloride is an embryonic ectoderm development (EED) inhibitor extracted from patent US20160176882 A1, compound example 2. MAK683 exhibits IC50s of 59, 89, 26 nM in EED Alphascreen binding, LC-MS and ELISA assay[1][2].

Name	MAK683 hydrochloride

Description	MAK683 hydrochloride is an embryonic ectoderm development (EED) inhibitor extracted from patent US20160176882 A1, compound example 2. MAK683 exhibits IC50s of 59, 89, 26 nM in EED Alphascreen binding, LC-MS and ELISA assay[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Epigenetics >> Histone Methyltransferase
References	[1]. Chan, Ho Man, et al. TRIAZOLOPYRIMIDINE COMPOUNDS AND USES THEREOF. US20160176882 A1. [2]. Huang D, et al. Binding Modes of Small-Molecule Inhibitors to the EED Pocket of PRC2. Chemphyschem. 2020 Feb 4;21(3):263-271.

Molecular Formula	C₂₀H₁₈ClFN₆O
Molecular Weight	412.85