2088545-68-8

2088545-68-8 structure

2088545-68-8 structure

Name: MPO-IN-4
Chemical Name: MPO-IN-4
CAS Number: 2088545-68-8
Molecular Formula: C₁₂H₁₁N₅
Molecular Weight: 225.25
Catalog: Research Areas Cardiovascular Disease
Create Date: 2022-05-31 17:58:26
Modify Date: 2024-01-16 11:16:22
MPO-IN-4 (compound 12) is a potent and selective myeloperoxidase (MPO) inhibitor with an IC500 of 25 nM. MPO-IN-4 has no effect on methyl guanine methyl transferase (MGMT)[1].

Name	MPO-IN-4

Description	MPO-IN-4 (compound 12) is a potent and selective myeloperoxidase (MPO) inhibitor with an IC500 of 25 nM. MPO-IN-4 has no effect on methyl guanine methyl transferase (MGMT)[1].
Related Catalog	Research Areas >> Cardiovascular Disease Research Areas >> Inflammation/Immunology
References	[1]. Scott A Shaw, et al. Discovery and structure activity relationships of 7-benzyl triazolopyridines as stable, selective, and reversible inhibitors of myeloperoxidase. Bioorg Med Chem. 2020 Nov 15;28(22):115723.

Molecular Formula	C₁₂H₁₁N₅
Molecular Weight	225.25