Shanghai Nianxing Industrial Co., Ltd
China
Product Name: MS5033
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: MS5033
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

2376137-29-8

2376137-29-8 structure

2376137-29-8 structure

Name: MS5033
Chemical Name: MS5033
CAS Number: 2376137-29-8
Molecular Formula: C₅₁H₆₆ClN₁₁O₁₁
Molecular Weight: 1044.59
Catalog: Signaling Pathways PI3K/Akt/mTOR Akt
Create Date: 2022-05-30 13:17:00
Modify Date: 2024-01-10 18:08:31
MS5033 is a potent PROTAC-based AKT (protein kinase B) degrader, with a DC50 of 430 nM in PC3 cells[1].

Name	MS5033

Description	MS5033 is a potent PROTAC-based AKT (protein kinase B) degrader, with a DC50 of 430 nM in PC3 cells[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PI3K/Akt/mTOR >> Akt Signaling Pathways >> PROTAC >> PROTAC
References	[1]. Yu XF, et, al. Discovery of Potent, Selective, and In Vivo Efficacious AKT Kinase Protein Degraders via Structure-Activity Relationship Studies. J Med Chem. 2022 Feb 24;65(4):3644-3666.

Molecular Formula	C₅₁H₆₆ClN₁₁O₁₁
Molecular Weight	1044.59

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