1257235-99-6
1257235-99-6 structure
- Name: NU5455
- Chemical Name: NU5455
- CAS Number: 1257235-99-6
- Molecular Formula: C34H33N3O5S
- Molecular Weight: 595.71
- Catalog: Signaling Pathways Cell Cycle/DNA Damage DNA-PK
- Create Date: 2022-05-21 17:52:49
- Modify Date: 2024-01-09 11:24:50
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NU5455 is a potent, selective, and orally active inhibitor of DNA-PKcs. NU5455 administration increases both the efficacy and the toxicity of a parenterally administered topoisomerase inhibitor. NU5455 enhances the activity of Doxorubicin released locally in liver tumor xenografts without inducing any adverse effect[1].
| Name | NU5455 |
|---|
| Description | NU5455 is a potent, selective, and orally active inhibitor of DNA-PKcs. NU5455 administration increases both the efficacy and the toxicity of a parenterally administered topoisomerase inhibitor. NU5455 enhances the activity of Doxorubicin released locally in liver tumor xenografts without inducing any adverse effect[1]. |
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| Molecular Formula | C34H33N3O5S |
|---|---|
| Molecular Weight | 595.71 |