2762279-02-5

2762279-02-5 structure

Name: ZDLD20
Chemical Name: ZDLD20
CAS Number: 2762279-02-5
Molecular Formula: C₂₂H₂₂N₆O
Molecular Weight: 386.45
Catalog: Signaling Pathways Cell Cycle/DNA Damage CDK
Create Date: 2022-05-21 07:38:02
Modify Date: 2024-01-20 18:08:13
ZDLD20, a β-carboline, is orally active and selective CDK4/CycD3 inhibitor with an IC50 value of 6.51 μM. ZDLD20 exhibits potent anti-HCT116 activity including inhibition of colony formation, inhibition of invasion and migration, inducing of apoptosis, and arresting of G1 phase in cell cycle. ZDLD20 exhibits potent anticancer activity[1].

Name	ZDLD20

Description	ZDLD20, a β-carboline, is orally active and selective CDK4/CycD3 inhibitor with an IC50 value of 6.51 μM. ZDLD20 exhibits potent anti-HCT116 activity including inhibition of colony formation, inhibition of invasion and migration, inducing of apoptosis, and arresting of G1 phase in cell cycle. ZDLD20 exhibits potent anticancer activity[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> CDK
Target	CDK4/CycD3:6.51 μM (IC50)
References	[1]. Deping Li, et al. Facile synthesis of C1-substituted β-carbolines as CDK4 inhibitors for the treatment of cancer. Bioorg Chem. 2022 Apr;121:105659.

Molecular Formula	C₂₂H₂₂N₆O
Molecular Weight	386.45