ZDLD20

Modify Date: 2024-01-20 18:08:13

ZDLD20 Structure
ZDLD20 structure
Common Name ZDLD20
CAS Number 2762279-02-5 Molecular Weight 386.45
Density N/A Boiling Point N/A
Molecular Formula C22H22N6O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of ZDLD20


ZDLD20, a β-carboline, is orally active and selective CDK4/CycD3 inhibitor with an IC50 value of 6.51  μM. ZDLD20 exhibits potent anti-HCT116 activity including inhibition of colony formation, inhibition of invasion and migration, inducing of apoptosis, and arresting of G1 phase in cell cycle. ZDLD20 exhibits potent anticancer activity[1].

 Names

Name ZDLD20

 ZDLD20 Biological Activity

Description ZDLD20, a β-carboline, is orally active and selective CDK4/CycD3 inhibitor with an IC50 value of 6.51  μM. ZDLD20 exhibits potent anti-HCT116 activity including inhibition of colony formation, inhibition of invasion and migration, inducing of apoptosis, and arresting of G1 phase in cell cycle. ZDLD20 exhibits potent anticancer activity[1].
Related Catalog
Target

CDK4/CycD3:6.51  μM (IC50)

References

[1]. Deping Li, et al. Facile synthesis of C1-substituted β-carbolines as CDK4 inhibitors for the treatment of cancer. Bioorg Chem. 2022 Apr;121:105659.

 Chemical & Physical Properties

Molecular Formula C22H22N6O
Molecular Weight 386.45
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