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1201673-28-0

1201673-28-0 structure
1201673-28-0 structure
  • Name: BPKDi
  • Chemical Name: BPKDi
  • CAS Number: 1201673-28-0
  • Molecular Formula: C21H28N6O
  • Molecular Weight: 380.49
  • Catalog: Signaling Pathways Apoptosis PKD
  • Create Date: 2022-07-01 11:14:12
  • Modify Date: 2024-01-10 15:56:48
  • BPKDi is a potent bipyridyl PKD inhibitor with IC50s of 1 nM, 9 nM and 1 nM for PKD1, PKD2 and PKD3, respectively. BPKDi blocks signal-dependent phosphorylation and nuclear export of class IIa HDACs in cardiomyocytes[1].

Name BPKDi
Description BPKDi is a potent bipyridyl PKD inhibitor with IC50s of 1 nM, 9 nM and 1 nM for PKD1, PKD2 and PKD3, respectively. BPKDi blocks signal-dependent phosphorylation and nuclear export of class IIa HDACs in cardiomyocytes[1].
Related Catalog
Target

PKD1:1 nM (IC50)

PKD2:9 nM (IC50)

PKD3:1 nM (IC50)

References

[1]. Lauren Monovich, et al. A novel kinase inhibitor establishes a predominant role for protein kinase D as a cardiac class IIa histone deacetylase kinase. FEBS Lett. 2010 Feb 5;584(3):631-7.

Molecular Formula C21H28N6O
Molecular Weight 380.49
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