1276197-57-9

1276197-57-9 structure

1276197-57-9 structure

Name: D(-)-2-Aminobutyric acid-d6
Chemical Name: D(-)-2-Aminobutyric acid-d6
CAS Number: 1276197-57-9
Molecular Formula: C₄H₃D₆NO₂
Molecular Weight: 109.16
Create Date: 2022-07-11 20:33:15
Modify Date: 2023-02-14 20:18:54
D(-)-2-Aminobutyric acid-d6 is the deuterium labeled D(-)-2-Aminobutyric acid. D(-)-2-Aminobutyric acid is a substrate of D-amino acid oxidase.

Name	D(-)-2-Aminobutyric acid-d6

Description	D(-)-2-Aminobutyric acid-d6 is the deuterium labeled D(-)-2-Aminobutyric acid. D(-)-2-Aminobutyric acid is a substrate of D-amino acid oxidase.
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Yagi K, et al. Spectroscopic demonstration of an initial stage of the complex of D-amino acid oxidase and its substrate D-alpha-aminobutyric acid. Biochem Biophys Res Commun. 1980 Nov 28;97(2):370-4.

Molecular Formula	C₄H₃D₆NO₂
Molecular Weight	109.16