1338575-38-4

1338575-38-4 structure

Name: FAAH-IN-5
Chemical Name: FAAH-IN-5
CAS Number: 1338575-38-4
Molecular Formula: C₂₁H₁₉N₃O₆S
Molecular Weight: 441.46
Catalog: Signaling Pathways Metabolic Enzyme/Protease FAAH
Create Date: 2022-06-15 20:39:13
Modify Date: 2026-07-15 18:25:27
FAAH-IN-5 (Compound 7) is a relative selective, irreversible fatty acid amide hydrolase (FAAH) inhibitor with an IC50 of 10.5 nM. FAAH-IN-5 shows low PAMPA (Parallel Artificial Membrane Permeability Assay) permeability[1].

Name	FAAH-IN-5
Synonyms	1-Piperazinecboxylic acid, 4-(2-naphthalenylsulfonyl)-, 4-nitrophenyl ester

Description	FAAH-IN-5 (Compound 7) is a relative selective, irreversible fatty acid amide hydrolase (FAAH) inhibitor with an IC50 of 10.5 nM. FAAH-IN-5 shows low PAMPA (Parallel Artificial Membrane Permeability Assay) permeability[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> MAGL Signaling Pathways >> Metabolic Enzyme/Protease >> FAAH Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> FAAH
Target	IC50: 10.5 nM (FAAH), 283 nM (MAGL)[1]
References	[1]. Alan Fulp, et al. Design and synthesis of endocannabinoid enzyme inhibitors for ocular indications. Bioorg Med Chem Lett. 2022 Jul 15;68:128763.

Molecular Formula	C₂₁H₁₉N₃O₆S
Molecular Weight	441.46