Shanghai Nianxing Industrial Co., Ltd
China
Product Name: ZINC194100678
Price: Check
Purity: 98.3%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

1995025-05-2

1995025-05-2 structure

1995025-05-2 structure

Name: ZINC194100678
Chemical Name: ZINC194100678
CAS Number: 1995025-05-2
Molecular Formula: C₁₀H₁₃N₅O
Molecular Weight: 219.24
Catalog: Signaling Pathways Cell Cycle/DNA Damage PAK
Create Date: 2022-06-29 22:44:36
Modify Date: 2024-01-03 10:51:19
ZINC194100678 is a potent PAK1 inhibitor with an IC50 value of 8.37 μM. ZINC194100678 can inhibit MDA-MB-231 cell proliferation. ZINC194100678 can be used for researching anticancer[1].

Name	ZINC194100678

Description	ZINC194100678 is a potent PAK1 inhibitor with an IC50 value of 8.37 μM. ZINC194100678 can inhibit MDA-MB-231 cell proliferation. ZINC194100678 can be used for researching anticancer[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cytoskeleton >> PAK Signaling Pathways >> Cell Cycle/DNA Damage >> PAK
Target	PAK1:8.37 μM (IC50)
In Vitro	ZINC194100678 (0-50 μM; 48 hours) exhibits potent antiproliferative activity with an IC50 value of 40.16 μM[1]. Cell Proliferation Assay Cell Line: MDA-MB-231[1] Concentration: 0-50 μM Incubation Time: 48 hours Result: Exhibited potent antiproliferative activity with an IC50 value of 40.16 μM.
References	[1]. Zhang J, et al. Design, synthesis and biological evaluation of 1H-pyrazolo [3,4-d]pyrimidine derivatives as PAK1 inhibitors that trigger apoptosis, ER stress and anti-migration effect in MDA-MB-231 cells. Eur J Med Chem. 2020;194:112220.

Molecular Formula	C₁₀H₁₃N₅O
Molecular Weight	219.24

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.