ZINC194100678

Modify Date: 2024-01-03 10:51:19

ZINC194100678 Structure
ZINC194100678 structure
Common Name ZINC194100678
CAS Number 1995025-05-2 Molecular Weight 219.24
Density N/A Boiling Point N/A
Molecular Formula C10H13N5O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of ZINC194100678


ZINC194100678 is a potent PAK1 inhibitor with an IC50 value of 8.37 μM. ZINC194100678 can inhibit MDA-MB-231 cell proliferation. ZINC194100678 can be used for researching anticancer[1].

 Names

Name ZINC194100678

 ZINC194100678 Biological Activity

Description ZINC194100678 is a potent PAK1 inhibitor with an IC50 value of 8.37 μM. ZINC194100678 can inhibit MDA-MB-231 cell proliferation. ZINC194100678 can be used for researching anticancer[1].
Related Catalog
Target

PAK1:8.37 μM (IC50)

In Vitro ZINC194100678 (0-50 μM; 48 hours) exhibits potent antiproliferative activity with an IC50 value of 40.16 μM[1]. Cell Proliferation Assay Cell Line: MDA-MB-231[1] Concentration: 0-50 μM Incubation Time: 48 hours Result: Exhibited potent antiproliferative activity with an IC50 value of 40.16 μM.
References

[1]. Zhang J, et al. Design, synthesis and biological evaluation of 1H-pyrazolo [3,4-d]pyrimidine derivatives as PAK1 inhibitors that trigger apoptosis, ER stress and anti-migration effect in MDA-MB-231 cells. Eur J Med Chem. 2020;194:112220.

 Chemical & Physical Properties

Molecular Formula C10H13N5O
Molecular Weight 219.24
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