2410443-42-2

2410443-42-2 structure
2410443-42-2 structure
  • Name: ZLN005-d4
  • Chemical Name: ZLN005-d4
  • CAS Number: 2410443-42-2
  • Molecular Formula: C17H14D4N2
  • Molecular Weight: 254.36
  • Catalog: Signaling Pathways Autophagy Autophagy
  • Create Date: 2022-07-07 22:05:03
  • Modify Date: 2024-01-10 14:23:06
  • ZLN005-d4 is deuterium labeled ZLN005. ZLN005 is a potent activator of peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α)[1].

Name ZLN005-d4
Description ZLN005-d4 is deuterium labeled ZLN005. ZLN005 is a potent activator of peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α)[1].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Zhang LN, et al. Novel small-molecule PGC-1α transcriptional regulator with beneficial effects on diabetic db/db mice. Diabetes. 2013 Apr;62(4):1297-307.

Molecular Formula C17H14D4N2
Molecular Weight 254.36