1644498-54-3
1644498-54-3 structure
- Name: THZ-2-118
- Chemical Name: THZ-2-118
- CAS Number: 1644498-54-3
- Molecular Formula: C28H27N7O2
- Molecular Weight: 493.571
- Create Date: 2022-07-01 10:04:26
- Modify Date: 2024-04-08 10:37:12
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THZ-2-118 is a potent selective inhibitor of IRAK1 with IC50 of 14.2 nM;THZ-2-118 does not inhibitor IRAK4 at 10 uM, also potently inhibits JNK1/2/3 (IC50=1-2 nM).
| Name | THZ-2-118 |
|---|
| Description | THZ-2-118 is a potent selective inhibitor of IRAK1 with IC50 of 14.2 nM;THZ-2-118 does not inhibitor IRAK4 at 10 uM, also potently inhibits JNK1/2/3 (IC50=1-2 nM). |
|---|---|
| References | 1. Hatcher JM, et al. ACS Med Chem Lett. 2020 Oct 9;11(11):2238-2243. |
| Molecular Formula | C28H27N7O2 |
|---|---|
| Molecular Weight | 493.571 |