Name | THZ-2-118 |
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Description | THZ-2-118 is a potent selective inhibitor of IRAK1 with IC50 of 14.2 nM;THZ-2-118 does not inhibitor IRAK4 at 10 uM, also potently inhibits JNK1/2/3 (IC50=1-2 nM). |
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References | 1. Hatcher JM, et al. ACS Med Chem Lett. 2020 Oct 9;11(11):2238-2243. |
Molecular Formula | C28H27N7O2 |
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Molecular Weight | 493.571 |