752237-67-5
752237-67-5 structure
- Name: BI-1915
- Chemical Name: BI-1915
- CAS Number: 752237-67-5
- Molecular Formula: C21H37N5O3
- Molecular Weight: 407.559
- Create Date: 2022-07-01 20:28:30
- Modify Date: 2025-08-25 13:03:55
-
BI-1915 (BI 1915) is a highly potent, selective inhibitor of Cathepsin S (CatS) with IC50 of 17 nM for in vitro use, no significant inhibition on Cathepsin L/K/B (IC50>10 uM);BI-1915 effectively blocks the specific ovalbumin induced IL-2 secretion in T-cells with an EC50 value of 2.8 nM.BI-1915 shows excellent selectivity against related cathepsins with IC50 values of >10 µM (Cat K and Cat B) and >30 µM (Cat L).
| Name | BI-1915 |
|---|
| Description | BI-1915 (BI 1915) is a highly potent, selective inhibitor of Cathepsin S (CatS) with IC50 of 17 nM for in vitro use, no significant inhibition on Cathepsin L/K/B (IC50>10 uM);BI-1915 effectively blocks the specific ovalbumin induced IL-2 secretion in T-cells with an EC50 value of 2.8 nM.BI-1915 shows excellent selectivity against related cathepsins with IC50 values of >10 µM (Cat K and Cat B) and >30 µM (Cat L). |
|---|
| Molecular Formula | C21H37N5O3 |
|---|---|
| Molecular Weight | 407.559 |