903886-95-3
903886-95-3 structure
- Name: A-908292
- Chemical Name: A-908292
- CAS Number: 903886-95-3
- Molecular Formula: C18H20N2O4S
- Molecular Weight: 360.428
- Catalog: Signaling Pathways Metabolic Enzyme/Protease Acetyl-CoA Carboxylase
- Create Date: 2022-06-27 18:26:34
- Modify Date: 2024-01-14 18:05:14
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A-908292 is a highly potent and selective acetyl-CoA carboxylase 2 (ACC2) inhibitor with IC50 of 38 nM (hACC2), no activity against ACC1 (IC50>30 uM).
| Name | A-908292 |
|---|
| Description | A-908292 is a highly potent and selective acetyl-CoA carboxylase 2 (ACC2) inhibitor with IC50 of 38 nM (hACC2), no activity against ACC1 (IC50>30 uM). |
|---|---|
| References | 1. Nishiura Y, et al. Bioorg Med Chem Lett. 2018 Aug 1;28(14):2498-2503. 2. Takagi H, et al. J Pharmacol Exp Ther. 2020 Mar;372(3):256-263. 3. Waring JF, et al. J Pharmacol Exp Ther. 2008 Feb;324(2):507-16. |
| Molecular Formula | C18H20N2O4S |
|---|---|
| Molecular Weight | 360.428 |